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A Randomized, Double-blind, Parallel Group, Multicenter, Phase III Study to Assess the Efficacy of Budesonide, Glycopyrronium, and Formoterol Fumarate Metered Dose Inhaler Relative to Glycopyrronium and Formoterol Fumarate MDI on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)

Rovia Lake City (ECIR Site)

This study is comparing how well BGF (brand name BREZTRI) or GFF (brand name BEVESPI) may help prevent COPD flare-ups and serious heart events in people with COPD. People with COPD have a higher risk of heart problems and serious heart events than people without COPD.

Inhaled corticosteroids (ICS) are known to help prevent COPD flare-ups. It is thought that combination treatments with inhaled corticosteroids (ICS) may help reduce serious heart events. For this reason, we will compare a treatment with an ICS (BGF) against one without an ICS (GFF).

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