This study is being done to see how safe an investigational drug is and how well it will work to help people with Body Mass Index (BMI) of greater than or equal to 27 kg/m2 and heart related and/or kidney related disease. “Investigational” means that the drug being tested has not been approved for routine clinical use or for the use described in this study by the United States Food and Drug Administration (FDA). The FDA is allowing the use of this study drug for research.
The main purpose of this study is to learn more about retatrutide (LY3437943), which is an investigational treatment for participants with Body Mass Index (BMI) of greater than or equal to 27 kg/m2 (kilogram per square meter) and heart related and/or kidney related disease.