Double-blind, placebo-controlled, phase 3 study to evaluate the efficacy and safety of plozasiran in adults with severe hypertriglyceridemia (SHASTA-3 study)
The purpose of this clinical research study is to look at how safe and effective ARO-APOC3 is at lowering triglycerides in people with hypertriglyceridemia. Hypertriglyceridemia is a condition where there is a high level of a certain kind of fat (called triglycerides) in the blood. The human body needs some triglycerides for good health. If […]
A Randomized, Double-blind, Parallel Group, Multicenter, Phase III Study to Assess the Efficacy of Budesonide, Glycopyrronium, and Formoterol Fumarate Metered Dose Inhaler Relative to Glycopyrronium and Formoterol Fumarate MDI on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)
This study is comparing how well BGF (brand name BREZTRI) or GFF (brand name BEVESPI) may help prevent COPD flare-ups and serious heart events in people with COPD. People with COPD have a higher risk of heart problems and serious heart events than people without COPD. Inhaled corticosteroids (ICS) are known to help prevent COPD […]
Continuous glucosemonitoring (CGM) in people with type 2 diabetes not on insulin: The CONNECT Study
The purpose of this research is to find out how well using Continuous Glucose Monitoring (CGM) works to improve glucose control compared to routine care (RC) in people with type 2 diabetes not taking insulin. Routine care for a person with type 2 diabetes is typically to check blood glucose by fingerstick at certain times […]
A Phase 3 Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-0616 in Reducing Major Adverse Cardiovascular Events in Participants at High Cardiovascular Risk
This trial is testing an experimental drug called MK-0616 in people with high cardiovascular risk. The purpose of this trial is to: A placebo looks like the trial drug, but it has no active ingredients.
