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The purpose of this study is to evaluate the effectiveness of 2 doses or 3 doses of GSK’s licenced meningococcal group B Bexsero (rMenB+OMV NZ) vaccine and of 2 doses of GSK’s investigational combined meningococcal (MenABCWY) vaccine (GSK3536819A) in healthy adolescents and young adults.
Location(s): Lake CIty
Condition: Vaccine
The purpose of this study is to determine if an AF detection intervention using a two week heart monitor in men and women at least 70 years of age with undiagnosed atrial fibrillation (AF) or atrial flutter (AFL) reduces the person-years incidence rate of stroke compared to usual care (no AF detection intervention).
Location(s): Jacksonville (Headquarters), Jacksonville- LaVilla (Downtown), Lake CIty
Condition: Heart Disease
This study compares insulin icodec (a new insulin taken once a week) to insulin glargine (an insulin taken once daily which is already available on the market) in people with type 2 diabetes.
Location(s): Jacksonville (Headquarters)
Condition: Diabetes
This is a phase 2 study is evaluating drug LY3209590 safety and effectiveness compared to insulin degludec in subjects with type 1 diabetes.
Location(s): Jacksonville- LaVilla (Downtown), Macon
Condition: Diabetes
This is a randomized, double-blind, placebo-controlled, dose-ranging Phase 2 study to evaluate the efficacy and safety of drug CIN-107 compared to placebo in patients with treatment-resistant hypertension (rHTN). The study will assess three oral doses of CIN-107 versus placebo.
Location(s): Jacksonville (Headquarters)
Condition: Resistant Hypertension
This study is evaluating the InterStim Micro system performance and safety to confirm long term outcomes
Location(s): Jacksonville (Headquarters)
Condition: Fecal Incontinence, Non-obstructive Urinary Retention, Overactive Bladder
This is a Phase 2a study being done to evaluate the efficacy, safety, PK, and immunogenicity of multiple doses of MEDI3506 in adult subjects with DKD.
Location(s): Jacksonville- LaVilla (Downtown)
Condition:
This study is being done to assess the efficacy and safety of tirzepatide compared to dulaglutide in patients with type 2 diabetes and increased cardiovascular risk.
Location(s): Jacksonville- LaVilla (Downtown), Macon
Condition: Diabetes, Heart Disease
ECO-RESET: is a Randomized, Double-Blind, Placebo-Controlled, Multiple Dose, Multi-center study to assess the efficacy and safety of SER‑287 in adults with active mild-to-moderate ulcerative colitis
Location(s): St. Augustine
Condition: Ulcerative Colitis
PRECISION: The study is to evaluate the blood pressure lowering effect of aprocitentan when added to other anti-hypertensive drugs of patients with difficult to control (resistant) high blood pressure (hypertension), and to show that blood pressure reduction is kept for long period of time.
Location(s): St. Augustine
Condition: Resistant Hypertension
This randomized, double-blind, placebo controlled, parallel group study being done to provide data on the efficacy, safety, tolerability and pharmacokinetics of multiple dose of PF-06882961 in adults with type 2 diabetes mellitus that are inadequately controlled on metformin and/or diet and exercise.
Location(s): Jacksonville (Headquarters), Jacksonville- LaVilla (Downtown), Macon
Condition: Diabetes
Protocol I8F-MC-GPHR(a) A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study Comparing the Efficacy and Safety of Tirzepatide versus Placebo in Patients with Nonalcoholic Steatohepatitis (NASH)
Location(s): Jacksonville- LaVilla (Downtown)
Condition: Nonalcoholic Steatohepatitis
The NODE-303 Study: Multi-Centre, Multi-National,Open Label, …
Location(s): St. Augustine
Condition:
SELECT – Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity
Location(s): Jacksonville (Headquarters)
Condition: Heart Disease
A Double-blind Randomized Placebo-controlled Trial Assessing the Effects of Inclisiran on Clinical Outcomes Among People With Atherosclerotic Cardiovascular Disease
Location(s): Jacksonville (Headquarters), Jacksonville- LaVilla (Downtown), Lake CIty, Macon, St. Augustine
Condition: Cholesterol, Heart Disease
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes (FOCUS)
Location(s): Jacksonville (Headquarters)
Condition: Diabetes