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The purpose of this phase 3 study is to evaluate glycemic control in participants with T2DM who are taking mealtime study insulin LY900014 in combination with long-acting insulin glargine.

Location(s): Macon

Condition: Diabetes

This phase 3 study is evaluating the efficacy and safety of study TQJ230 compared to placebo in the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a).

Location(s): Jacksonville (Headquarters), St. Augustine

Condition: Heart Disease

The purpose of this phase 3 study is to evaluate the effect of finerenone compared to placebo in the reduction of cardiovascular death and total Heart Failure events, including HF hospitalization and urgent visits for HF in patients suffering from HF with an ejection fraction greater than or equal to 40%.

Location(s): St. Augustine

Condition: Heart Failure

The purpose of this phase 2 study is to evaluate the bleeding profile of abelacimab compared to rivaroxaban in patients with atrial fibrillation (AF) at moderate-to-high risk of stroke.

Location(s): Jacksonville (Headquarters), St. Augustine

Condition: Atrial Fibrillation, Heart Disease

The purpose of this phase 3 study is to evaluate the safety and effects of study tirzepatide on body weight compared to placebo T2DM patients who are overweight or obese.

Location(s): Macon

Condition: Diabetes, Obese/Obesity

The purpose of the study is to evaluate the dose-response efficacy, safety, and pharmacokinetics (PK) of AZD5718 compared to placebo in participants with proteinuric chronic kidney disease (CKD).

Location(s): Macon

Condition: Kidney Disease

This is a phase 2 study evaluating the efficacy and safety of a low and high dose of study LX9211 compared to placebo in patients with moderate to severe diabetic peripheral neuropathy.

Location(s): Jacksonville- LaVilla (Downtown), Lake CIty, Macon

Condition: Diabetic Peripheral Neuropathy

This is a randomized, double-blind, placebo-controlled Phase 2 study to evaluate the efficacy and safety of drug IONIS-AGT-LRx compared to placebo in patients with treatment-resistant hypertension (rHTN).

Location(s): Jacksonville (Headquarters), St. Augustine

Condition: Resistant Hypertension

This is a phase 2 study evaluating drug LY3437943 safety and effectiveness compared to placebo in subjects who are overweight or obese patients.

Location(s): Jacksonville (Headquarters)

Condition: Overweight/Obesity

The purpose of this study is to evaluate the effectiveness of 2 doses or 3 doses of GSK’s licenced meningococcal group B Bexsero (rMenB+OMV NZ) vaccine and of 2 doses of GSK’s investigational combined meningococcal (MenABCWY) vaccine (GSK3536819A) in healthy adolescents and young adults.

Location(s): Lake CIty

Condition: Vaccine

This study compares insulin icodec (a new insulin taken once a week) to insulin glargine (an insulin taken once daily which is already available on the market) in people with type 2 diabetes.

Location(s): Jacksonville (Headquarters)

Condition: Diabetes

This is a randomized, double-blind, placebo-controlled, dose-ranging Phase 2 study to evaluate the efficacy and safety of drug CIN-107 compared to placebo in patients with treatment-resistant hypertension (rHTN). The study will assess three oral doses of CIN-107 versus placebo.

Location(s): Jacksonville (Headquarters)

Condition: Resistant Hypertension

This study is evaluating the InterStim Micro system performance and safety to confirm long term outcomes

Location(s): Jacksonville (Headquarters)

Condition: Fecal Incontinence, Non-obstructive Urinary Retention, Overactive Bladder

This is a Phase 2a study being done to evaluate the efficacy, safety, PK, and immunogenicity of multiple doses of MEDI3506 in adult subjects with DKD.

Location(s): Jacksonville- LaVilla (Downtown)

Condition:

This study is being done to assess the efficacy and safety of tirzepatide compared to dulaglutide in patients with type 2 diabetes and increased cardiovascular risk.

Location(s): Jacksonville- LaVilla (Downtown), Macon

Condition: Diabetes, Heart Disease

A Double-blind Randomized Placebo-controlled Trial Assessing the Effects of Inclisiran on Clinical Outcomes Among People With Atherosclerotic Cardiovascular Disease

Location(s): Jacksonville (Headquarters), Jacksonville- LaVilla (Downtown), Lake CIty, Macon, St. Augustine

Condition: Cholesterol, Heart Disease

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes (FOCUS)

Location(s): Jacksonville (Headquarters)

Condition: Diabetes